Inhalable nanoparticles to the heart
Inhalable nanoparticles to the heart
Nanotechnology meets cardiology
Nanotechnology meets cardiology
A drug-delivery as simple as breathing
A drug-delivery as simple as breathing
Background
Our Goal
Consortium

THE BREATHING HEART

1. Nanoparticle production
Biocompatible and biodegradable nanoparticles can self-assemble and encapsulate drugs
2. Inhalation
Nanoparticles are transformed into an inhalable coarser dry powder that can reach the airways.
3. Crossing the pulmonary barrier
Nanoparticles can cross the alveolar-capillary barrier, rapidly reaching the heart
4. One target: the heart
The heart specificity is ensured thanks to chemical and magnetic guidance

THE CONSORTIUM

99
Research groups
99
SMEs
99
Pharma Company
99
Industries

A multidisciplinary team

CUPIDO multidisciplinary consortium gathers a heterogeneous array of expertise and pulls together cutting-edge research with pre-clinical experience and industrial manufacturing. Indeed the 12 CUPIDO partners can cover the complete chain that brings an idea into a feasible product and cover expertise in:

  • cardiovascular and nanotechnology research
  • bioengineering and molecular imaging
  • pulmonology and lung cell biology
  • in silico computational models
  • wearable electronics
  • drug delivery solutions
  • pharmaceutical products.
CUPIDO’s videos

NEWS

Biodistribution in vivo
Biodistribution in vivo
February 21, 2020
The CUPIDO final product owns a certain technological complexity because it consists of two parts: the calcium phosphate nanoparticles that act as nano-carrier and the cardiac-specific drug,...
Modelling perfusion in the human heart
Modelling perfusion in the human heart
November 17, 2019
Heart tissue is perfused by thousands of very small arteries and capillaries branching off the coronary arteries. Obtaining truthful representations of the exact geometries of the perfusion ...
Imaging of the nanoparticle’s distribution in animal models
Imaging of the nanoparticle’s distribution in animal models
November 6, 2019
One of the key issues in CUPIDO is to track where and when the inhaled CaP nanoparticles travel in the body in vivo (biodistribution). As a first approach, the imaging studies, performed by ...
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